IOPtima CO2 Laser-Assisted Sclerectomy Surgery (CLASS):

IOPtima Ltd. has developed the IOPtimate system, a unique CO2 laser-assisted system for the treatment of Glaucoma.

The IOPtimate system is intended to treat patients with primary Open-Angle Glaucoma (POAG) and Pseudo-Exfoliative Glaucoma (PEXG). Notwithstanding, IOPtima has already accumulated a very positive experience in combined surgeries (Cataract and Glaucoma).

In utilizing the particular properties of the CO2 laser, the IOPtimate system, thins the sclera wall via ablating surges at the Schlemm’s Canal area without penetrating the scleral wall, thereby reducing IOP by facilitating adequate, functional percolation of intra-ocular fluid from the eye through the remaining membrane in a simple and highly controlled and specific manner.

As infrared CO2 laser radiation is absorbed and blocked by water and aqueous solutions, it is therefore ineffective in ablating when applied over wet tissues, thus does not allow the procedure to penetrate into the eye like other invasive procedures.

Therefore, the remaining thin scleral layer remains intact, without penetration into the eye, which is known to be the source of most ophthalmic surgery complications, adverse events and side effects.

CLASS Principle of Operation:


The CLASS procedure requires local anesthesia, is performed as an outpatient procedure and has minimal side effects, which are for the most part transient. At the same time, the CLASS procedure is highly efficacious, with a minimal learning curve.

Differentiation from Trabeculectomy

Unlike Trabeculectomy, CLASS is non-invasive by nature and does not result in the perforation of any tissue. CLASS provides surgeons with enhanced control, regulation and therefore safety during the surgery. Because CLASS doesn’t penetrate into the eye like Trabeculectomy, the level of complications or potential side effects is much lower and the postoperative care following surgery requires significantly less office visits.

Differentiation from Minimally-Invasive Devices (Shunts, GDD’s)

These stent-like devices were developed in order to regulate the manual trabeculectomy, creating a standardized canal for Aqueus Humor percolation. However, these are foreign bodies which can migrate, encourage inflammation and in some rare cases get blocked.